Procarbazine hydrochloride

CAS No. 366-70-1

Procarbazine hydrochloride ( Indicarb; Matulane; Natulan; NSC 77213 )

Catalog No. M14259 CAS No. 366-70-1

Procarbazine hydrochloride (Matulane) is a hydrochloride salt form of procarbazine which is a polyfunctional alkylating compound used as an antineoplastic agent.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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200MG 57 In Stock
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Biological Information

  • Product Name
    Procarbazine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Procarbazine hydrochloride (Matulane) is a hydrochloride salt form of procarbazine which is a polyfunctional alkylating compound used as an antineoplastic agent.
  • Description
    Procarbazine hydrochloride (Matulane) is a hydrochloride salt form of procarbazine which is a polyfunctional alkylating compound used as an antineoplastic agent. Procarbazine is a cytostatic agent, meaning it strands cells midway through cell division, but it does not actively kill them. Procarbazine interferes with cells at a number of sites to prevent DNA and protein synthesis and mitosis. Procarbazine hydrochloride (Matulane) is used in the treatment of Hodgkin’s lymphoma and other malignant lymphomas including:- lymphosarcoma- reticulosarcoma- Brill-Symmers disease. Because procarbazine hydrochloride (Matulane) works differently to other anticancer agents,Procarbazine hydrochloride (Matulane) may be useful in the treatment of Ys that have not responded to other treatments.
  • Synonyms
    Indicarb; Matulane; Natulan; NSC 77213
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    366-70-1
  • Formula Weight
    257.76
  • Molecular Formula
    C12H19N3O·HCl
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 52 mg/mL (201.73 mM); Water: 52 mg/mL (201.73 mM)
  • SMILES
    Cl.CNNCC1=CC=C(C=C1)C(=O)NC(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ogawa K, et al. Mutat Res. 2003 Aug 5;539(1-2):145-55.
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